Invivotek offers bioassays to measure different aspects or modalities of pain and surgical models of neuropathic pain that can be used for phenotypic characterization of genetically modified rodents.
Hargreave’s Tail Flick
Chemically-induced Inflammatory Pain
Acetic Acid-induced Writhing Test
Complete Freund’s Adjuvant Challenge
Formalin Pain Assay
von Frey Test
Neuropathic Pain Models
Chronic Constrictive Injury (CCI) Model
Partial Sciatic Nerve Ligation (PNL) Model
Tibial Nerve Transection (TNT) Model
We recommend an evaluation of locomotor activity in the Open Field and/or Rotarod test in conjunction with Pain Assays to discriminate decreased pain responses from potential motor impairments.