Invivotek

Phenotypic Characterization Program


Applications

  • Target validation

  • Liability Assessment

  • New indications discovery

Phenotypic characterization of genetically-modified animals plays a critical role in the drug target validation process. The research needs of our clients vary depending on the stage and specific goals of a drug discovery and development program. Our scientific experts work with every client to custom-design each phenotyping project to best meet our clients’ needs and to provide interpretive data analysis at the end of each study.

More Data + Fewer Animals + Less Time = Greater Value


Our Phenotyping Program:

  • Includes 90+ bioassays relevant to most therapeutic areas

  • Uses 90% fewer mice due to multiplexing validated panels of assays

  • Includes complete statistical analysis and data interpretation

We offer an in-depth disease–oriented phenotyping assessment with an emphasis on autoimmune and inflammatory disorders, metabolism, diabetes and obesity. In addition, by multiplexing bioassays spanning multiple therapeutic areas, we provide a powerful tool for assessment of potential on-target side effects and early identification of new therapeutic indications for genetic targets. Sequential evaluation of animals in predesigned and validated bioassay combinations maximizes the data set per animal achieving significant savings in time and cost for our clients.

Invivotek’s team has experience with over 90 standardized and validated bioassays to support pre-clinical research related to treatments in the following:

Your Success Is Our Priority


We understand the importance of meeting deadlines and maintaining high quality standards. We work with our clients to define all of the critical steps for project optimization and success:

  • Define project scope

  • Set project goals, create timelines and establish milestones

  • Issue status reports for each milestone

  • Provide a final study report at project completion

  • Autoimmune Diseases

  • Cardiovascular Diseases

  • Diabetes

  • Inflammation

  • Neurodegenerative Disorders

  • Pain

  • Obesity

  • Oncology

  • Psychiatric Disorders

  • Respiratory disorders

  • Sexual Health